Article ID Journal Published Year Pages File Type
3277710 Nutrition 2007 6 Pages PDF
Abstract

ObjectiveWe assessed the effects of an intervention aimed at increasing the consumption of fruits and vegetables on plasma folate and homocysteine concentrations.MethodsSeventy-one healthy non-smoking women (mean ± SD 41 ± 4 y of age) were randomized to an intervention or a control group. Participants in the intervention group (n = 36) received weekly packets containing fruits and vegetables free of charge and were asked to consume a daily amount of ≥200 g of vegetables and two pieces of fruit (the Dutch recommended intake level) over a period of 1 mo. Control subjects did not receive any intervention.ResultsCompared with the control group, reported fruit and vegetable intakes in the intervention group increased by 133 g/d (95% confidence interval [CI] 87–179, P < 0.001) for fruits and juice and 64 g/d (95% CI 37–91, P < 0.001) for vegetables and estimated folate intake from fruits and vegetables increased by 40 μg/d (95% CI 22–58, P < 0.001). However, no effect was observed on plasma folate concentrations (intervention effect 0.3 nmol/L, 95% CI −1.8 to 2.8, P = 0.77) or homocysteine concentrations (intervention effect 0.26 μmol/L, 95% CI −0.34 to 0.87, P = 0.39).ConclusionThe results suggest that 4 wk of increased fruit and vegetable consumption to the recommended amounts may be insufficient to change plasma folate and homocysteine concentrations.

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Health Sciences Medicine and Dentistry Endocrinology, Diabetes and Metabolism
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