Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
327795 | Journal of Psychiatric Research | 2010 | 4 Pages |
Abstract
Choudhury et al. identified FXYD6 as a susceptible gene for schizophrenia in the London and Aberdeen populations. We genotyped D11S1998 and 8 SNPs (rs869789, rs11216567, rs10790212, rs876797, rs4938445, rs497768, rs11216598, rs11605223) in a Chinese sample consisting of 1514 schizophrenia patients and 1514 healthy controls. We also compared the expression levels of FXYD6 in lymphocytes in 86 schizophrenia patients and 94 controls. No association was detected either in D11S1998 or the 8 SNPs. No difference was found in expression level between patients and controls. Our study suggests that FXYD6 does not play a role in schizophrenia in the Chinese Han population.
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Authors
Jing Zhang, Ronglin Che, Xingwang Li, Wei Tang, Qian Zhao, Ruqi Tang, Yang Wang, Zhao Zhang, Jue Ji, Fengping Yang, Yongyong Shi, Weidong Ji, Guoquan Zhou, Guoyin Feng, Lin He, Guang He,