| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3281403 | Clinical Gastroenterology and Hepatology | 2016 | 9 Pages |
Abstract
MMR deficiency in colorectal tumors occurs with similar rates among patients of different racial and ethnic groups, which is based on immunohistochemical analysis of 253 primary tumor specimens. This finding indicates the potential value of universal testing of colorectal cancer by immunohistochemistry in minority populations and confirms the benefit of MMR deficiency to OS.
Keywords
NAACCRMSI-HNHWADCMSSMSIMMRAJCCFFPEAdenocarcinomaHispanicMinorityIHCimmunohistochemicaloverall survivalMicrosatellite instabilitymismatch repairDNA mismatch repairmicrosatellite stableColorectal cancerNon-Hispanic whiteLynch syndromeblackconfidence intervalformalin-fixed paraffin-embeddedhazard ratioodds ratioCRCAmerican Joint Committee on Cancer
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Authors
Shivali Berera, Tulay Koru-Sengul, Feng Miao, Olveen Carrasquillo, Mehrdad Nadji, Yaxia Zhang, Peter J. Hosein, Jacob L. McCauley, Maria T. Abreu, Daniel A. Sussman,