| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3281637 | Clinical Gastroenterology and Hepatology | 2014 | 11 Pages |
Abstract
The integrity of the esophageal mucosa is impaired in patients with EoE and PPI-REE, allowing transepithelial transport of small molecules. PPI therapy partially restores mucosal integrity in patients with PPI-REE, but not in those with EoE. Acid reflux might contribute to transepithelial allergen flux in patients with PPI-REE. Trialregister.nl number: NTR3480.
Keywords
Eotaxin-3CCL26PPIFLGIQRPPI-REEeos/hpfGERDEoEEoE, Eosinophilic esophagitisinterleukingastroesophageal reflux diseaseTERTreatmentfilaggrinEpithelial barrierinterquartile rangeTransepithelial resistancetransepithelial electrical resistanceProton pump inhibitorpolymerase chain reactionPCRPathophysiologyPeriostinPostn
Related Topics
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Authors
Bram D. van Rhijn, Pim W. Weijenborg, Joanne Verheij, Marius A. van den Bergh Weerman, Caroline Verseijden, René M.J.G.J. van den Wijngaard, Wouter J. de Jonge, Andreas J.P.M. Smout, Albert J. Bredenoord,