Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3282403 | Clinical Gastroenterology and Hepatology | 2015 | 16 Pages |
Abstract
Hepatomegaly is common even in early stage ADPKD and is not accounted for by cysts alone. Parenchymal volumes were larger, compared with liver volumes of patients without ADPKD or with those predicted by standardized equations, even among patients without cysts. The severity of PLD was associated with altered biochemical and hematologic features, as well as quality of life. ClinicalTrials.gov identifier: NCT00283686.
Keywords
ALTLPVADPKDSF-36HTLVQOLLCVMRI analysisPLDEGFRQuality of lifeAlanine aminotransferaseALPAlkaline phosphataseMRIpolycystic liver diseaseautosomal-dominant polycystic kidney diseaseMagnetic resonance imagingbody mass indexBMIshort-form 36Blood pressureestimated glomerular filtration rateCKDtotal liver volumeHepatic cyst
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Authors
Marie C. Hogan, Kaleab Abebe, Vicente E. Torres, Arlene B. Chapman, Kyongtae T. Bae, Cheng Tao, Hongliang Sun, Ronald D. Perrone, Theodore I. Steinman, William Braun, Franz T. Winklhofer, Dana C. Miskulin, Frederic Rahbari-Oskoui, Godela Brosnahan,