Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3282460 | Clinical Gastroenterology and Hepatology | 2013 | 7 Pages |
Abstract
The TNF antagonists IFX and ADA are transferred across the placenta and can be detected in infants at birth; the drugs were detected in infants up to 6 months after birth. CZP has the lowest level of placental transfer, based on levels measured in cords and infants at birth, of the drugs tested.
Keywords
IBDTNFCertolizumab pegolAdalimumabIFXCZPBCGnuclear magnetic resonanceBacillus Calmette–GuérinSafetyimmunoglobulin InfliximabPregnancyNICUCrohn's diseaseInflammatory bowel diseaseEnzyme-linked immunosorbent assayELISANMRTreatmenttumor necrosis factorneonatal intensive care unitADApolyethylene glycolPEGPianoUlcerative colitis
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Authors
Uma Mahadevan, Douglas C. Wolf, Marla Dubinsky, Antoine Cortot, Scott D. Lee, Corey A. Siegel, Thomas Ullman, Sarah Glover, John F. Valentine, David T. Rubin, Jocelyn Miller, Maria T. Abreu,