Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3282916 | Clinical Gastroenterology and Hepatology | 2012 | 4 Pages |
Abstract
Celiac disease (CD) is an autoimmune enteropathy that occurs in genetically susceptible individuals carrying the prerequisite genetic markers HLA DQ2 or DQ8. These genetic markers are present in approximately 30% of the population, and the worldwide prevalence of CD is estimated to be approximately 1%-2%. Currently a gluten-free diet is the only treatment for CD, but novel therapies aimed at gluten modification are underway. This review will discuss gluten-based therapies including wheat alternatives and wheat selection, enzymatic alteration of wheat, oral enzyme supplements, and polymeric binders as exciting new therapies for treatment of CD.
Keywords
Related Topics
Health Sciences
Medicine and Dentistry
Gastroenterology
Authors
Samantha Stoven, Joseph A. Murray, Eric Marietta,