| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3283077 | Clinical Gastroenterology and Hepatology | 2012 | 10 Pages |
Abstract
Patients with IBS-D have greater body mass index and synthesize and excrete higher levels of BA than individuals with IBS-C or healthy volunteers. Serum levels of C4 might be used to identify patients with IBS-D who have BA malabsorption; studies are needed to determine if some patients have a genetic predisposition to this disorder.
Keywords
IQRIBSIBS-DIBS-CMAFFGFR4FGF7α-hydroxy-4-cholesten-3-oneBile acidBAMHealthy volunteersdiarrhea-predominant irritable bowel syndromeirritable bowel syndromebody mass indexBMIBile acid malabsorptionfibroblast growth factorMalabsorptionminor allele frequenciesMetabolisminterquartile rangesSingle nucleotide polymorphismSNPLiverKlbColonfibroblast growth factor receptor 4Constipation-predominant irritable bowel syndrome
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Authors
Banny S. Wong, Michael Camilleri, Paula Carlson, Sanna McKinzie, Irene Busciglio, Olga Bondar, Roy B. Dyer, Jesse Lamsam, Alan R. Zinsmeister,