Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3283117 | Clinical Gastroenterology and Hepatology | 2012 | 9 Pages |
Abstract
Steatosis, portal inflammation, and fibrosis are less severe during or after puberty than before puberty among subjects with NAFLD. Postpubescent individuals have a lower prevalence of borderline steatohepatitis of zone 1 but are more likely to have Mallory-Denk bodies. These findings indicate that puberty affects the pathologic features of NAFLD.
Keywords
NAFLDACORNASH CRNAORQUICKIHDLIFGhigh-density lipoproteinImpaired fasting glucosenonalcoholic steatohepatitisstandard deviationNonalcoholic fatty liver diseaseanalysis of varianceANOVASexual developmentTonicbody mass indexBMIquantitative insulin sensitivity check indexnonalcoholic steatohepatitis clinical research networkLow-density lipoproteinLDLObesityMETadjusted odds ratioNash Sex hormonesMetabolic equivalent tasks
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Authors
Ayako Suzuki, Manal F. Abdelmalek, Jeffrey B. Schwimmer, Joel E. Lavine, Ann O. Scheimann, Aynur Unalp-Arida, Katherine P. Yates, Arun J. Sanyal, Cynthia D. Guy, Anna Mae Diehl,