Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3283261 | Clinical Gastroenterology and Hepatology | 2011 | 8 Pages |
Abstract
HVPG is an independent predictor of response to antiviral therapy, with better predictive value than liver stiffness, baseline HCV RNA levels, HCV genotype, or IL-28B polymorphism. The incidence and grade of thrombocytopenia during antiviral therapy are higher among patients with CSPH. In evaluating cirrhotic HCV patients for antiviral treatment, measurement of HVPG should be considered.
Keywords
CSPHRVRHVPGRBVPEG-IFNANCAUROCAUCPegylated interferoninterleukinclinically significant portal hypertensionLiver diseaseAbsolute neutrophil countRibavirinPortal pressureFibrosisModel of End-stage Liver Diseasearea under the curveArea under the receiver operating characteristicHemoglobinHepatitis C virusHCVTreatment responserapid virologic responseSingle nucleotide polymorphismSNPMELD
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Authors
Thomas Reiberger, Karoline Rutter, Arnulf Ferlitsch, Berit Anna Payer, Harald Hofer, Sandra Beinhardt, Michael Kundi, Peter Ferenci, Alfred Gangl, Michael Trauner, Markus Peck-Radosavljevic,