Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3284069 | Clinical Gastroenterology and Hepatology | 2010 | 10 Pages |
Abstract
Response to open-label induction therapy with certolizumab pegol was achieved by 62% of patients with moderate to severely active Crohn's disease and secondary failure to infliximab. Among these patients, certolizumab pegol 400 mg every 4 weeks showed similar efficacy to every-2-weeks dosing for maintenance of response and remission.
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Authors
William J. Sandborn, Maria T. Abreu, Geert D'Haens, Jean-Frédéric Colombel, Severine Vermeire, Krassimir Mitchev, Corinne Jamoul, Richard N. Fedorak, Martina E. Spehlmann, Douglas C. Wolf, Scott Lee, Paul Rutgeerts,