Elevated Soluble Tumor Necrosis Factor Receptor 75 Concentrations Identify Patients With Liver Cirrhosis at Risk of Death

Article ID	Journal	Published Year	Pages	File Type
3284857	Clinical Gastroenterology and Hepatology	2008	8 Pages	PDF

Abstract

Elevated sTNF-R 75 levels independently predicted mortality and improved MELD on the basis of evaluation of prognosis, especially in patients with high MELD scores. Thus, sTNF-R 75 levels might be a useful cytokine-based prognostic marker in patients with liver cirrhosis.

Keywords

sTNF-R Child-Turcotte-Pugh CTP ROC NYHA INR nuclear magnetic resonance AUC New York Heart Association NMR Tumor necrosis factor–alpha Coefficient of Variation confidence interval TNF-α Model for End-Stage Liver Disease area under the curve International Normalized Ratio MELD receiver operating characteristic

Related Topics

Health Sciences Medicine and Dentistry Gastroenterology

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Elevated Soluble Tumor Necrosis Factor Receptor 75 Concentrations Identify Patients With Liver Cirrhosis at Risk of Death

Authors

Frank Grünhage, Bettina Rezori, Markus Neef, Frank Lammert, Tilman Sauerbruch, Ulrich Spengler, Christoph Reichel,