| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3286195 | Clinics and Research in Hepatology and Gastroenterology | 2015 | 7 Pages |
SummaryBackground and objectiveIt is widely accepted that conventional 18F-FDG PET/CT (whole-body static 18F-FDG PET/CT, WB 18F-FDG PET/CT) has a low detection rate for hepatocellular carcinoma (HCC). We prospectively assessed the role of early dynamic 18F-FDG PET/CT (ED 18F-FDG PET/CT) and WB 18F-FDG PET/CT in detecting HCC, and we quantified the added value of ED 18F-FDG PET/CT to WB 18F-FDG PET/CT.MethodsTwenty-two patients with 37 HCC tumors (HCCs) who underwent both a liver ED 18F-FDG PET/CT (performed simultaneously with a 5.5 MBq/kg 18F-FDG bolus injection and continued for 240 s) and a WB 18F-FDG PET/CT were enrolled in the study.ResultsThe WB 18F-FDG PET/CT and ED 18F-FDG PET/CT scans were positive in 56.7% (21/37) and 78.4% (29/37) HCCs, respectively (P < 0.05). ED 18F-FDG PET/CT in conjunction with WB 18F-FDG PET/CT (one-stop 18F-FDG PET/CT) improved the positive detection rates of WB and ED 18F-FDG PET/CT alone from 56.7% and 78.4% to 91.9% (34/37) (P < 0.001 and P > 0.05, respectively).ConclusionOne-stop 18F-FDG PET/CT appears to be useful to improve WB 18F-FDG PET/CT for HCC detection.
