| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3291864 | Gastroenterology | 2016 | 24 Pages |
Abstract
Our study highlights a major role for RNA editing in GC disease and progression, an observation potentially missed by previous next-generation sequencing analyses of GC focused on DNA alterations alone. Our findings also suggest new GC therapeutic opportunities through ADAR1 enzymatic inhibition or the potential restoration of ADAR2 activity.
Keywords
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Gastroenterology
Authors
Tim Hon Man Chan, Aditi Qamra, Kar Tong Tan, Jing Guo, Henry Yang, Lihua Qi, Jaymie Siqi Lin, Vanessa Hui En Ng, Yangyang Song, Huiqi Hong, Su Ting Tay, Yujing Liu, Jeeyun Lee, Sun Yong Rha, Feng Zhu, Jimmy Bok Yan So, Bin Tean Teh, Khay Guan Yeoh,