| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3291924 | Gastroenterology | 2016 | 41 Pages |
Abstract
In this large-scale GWAS of gallstone disease, we identified 4 loci in genes that have putative functions in cholesterol metabolism and transport, and sulfonylation of bile acids or hydroxysteroids.
Keywords
GCKRRPKMGCTAGRsMAFeQTLARICNHSFHSHPFsWomen’s Health InitiativeHealth Professionals Follow-up Studyreads per kilobase per millionExpression quantitative trait lociAtherosclerosis Risk in Communities StudyICDbody mass indexBMIInternational Classification of DiseasesRisk factorsconfidence intervalsminor allele frequencyGenome-wide association studiesStudy of Health in PomeraniaNurses’ Health StudyFramingham Heart StudyGWASodds ratiogenetic risk scorewhiGlucokinase regulatory proteinSingle-nucleotide polymorphismSNPGeneticsSHIP
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Authors
Amit D. Joshi, Charlotte Andersson, Stephan Buch, Stefan Stender, Raymond Noordam, Lu-Chen Weng, Peter E. Weeke, Paul L. Auer, Bernhard Boehm, Constance Chen, Hyon Choi, Gary Curhan, Joshua C. Denny, Immaculata De Vivo, John D. Eicher, David Ellinghaus,