| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3292197 | Gastroenterology | 2016 | 26 Pages |
Abstract
Expression of activated Ras in chief cells of Mist1-Kras mice led to the full range of metaplastic lineage transitions, including SPEM and IM. Inhibition of Ras signaling by inhibition of MEK might reverse preneoplastic metaplasia in the stomach.
Keywords
DABGFPGriffonia simplicifolia lectin IIERKGSIIDMSOSPEMTffalcian blueperiodic acid–SchiffDifferentiationDimethyl sulfoxideCarcinogenesistrefoil factorspasmolytic polypeptide-expressing metaplasiaIntestinal metaplasiaPASSignal transductiongreen fluorescent proteinMAP kinaseExtracellular signal–regulated kinase
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Authors
Eunyoung Choi, Audrey M. Hendley, Jennifer M. Bailey, Steven D. Leach, James R. Goldenring,