| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3292265 | Gastroenterology | 2015 | 13 Pages |
Abstract
Direct-acting antiviral-mediated clearance of HCV is associated with loss of intrahepatic immune activation by IFNα, which is indicated by decreased levels of CXCL10 and CXCL11 and normalization of NK cell phenotype and function.
Keywords
ASVCXCLRBVdcvDAAISGIQRAPCphosphorylated signal transducer and activator of transcriptionEMAMFIFITCPBMCpStatFBSTNFnatural killerEOTasunaprevirallophycocyaninSTATEthidium monoazideDirect-acting antiviralinterferonIFNinterleukindaclatasvirRibavirinfetal bovine serumNS5A Inhibitortumor necrosis factorfluorescein isothiocyanateTRAILSignal transducer and activator of transcriptioninterquartile rangeImmune regulationmean fluorescence intensityHepatitis C virusHCVend of treatmentinterferon-stimulated gene
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Authors
Elisavet Serti, Xenia Chepa-Lotrea, Yun Ju Kim, Meghan Keane, Nancy Fryzek, T. Jake Liang, Marc Ghany, Barbara Rehermann,