| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3292670 | Gastroenterology | 2014 | 19 Pages |
Abstract
Inflammatory CD28- T cells accumulate in livers of patients with PSC and localize around bile ducts. The TNFα-rich microenvironment of this tissue promotes inflammation; these effects are reversed by vitamin D in vitro.
Keywords
PBMCTIM3CXCRPBCIFNγTregICAM1TNFαCCRPSCBECC-C chemokine receptornonalcoholic steatohepatitisinterferoninterferon γinterleukintumor necrosis factor αautoimmunitybiliary epithelial cellPeripheral blood mononuclear cellT regulatory cellbiliary epithelial cellsPrimary biliary cirrhosisImmune regulationintercellular cell adhesion molecule-1Nash Primary sclerosing cholangitisDisease control
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Authors
Evaggelia Liaskou, Louisa E. Jeffery, Palak J. Trivedi, Gary M. Reynolds, Shankar Suresh, Tony Bruns, David H. Adams, David M. Sansom, Gideon M. Hirschfield,