| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3292840 | Gastroenterology | 2014 | 25 Pages |
Abstract
LL-IL-27 reduces colitis in mice by increasing the production of IL-10. Mucosal delivery of LL-IL-27 could be a more effective and safer therapy for inflammatory bowel disease.
Keywords
PBSMLNLALEBI3DAIIBDLimulus Amebocyte LysateDSSmRNALPSIELmessenger RNAinterferonIFNinterleukinCrohn's diseaseInflammatory bowel diseaseGastrointestinaldouble positiveSmall intestineT-helper cellDextran sulfate sodiumdisease activity indexLactococcus lactisIntraepithelial lymphocytelipopolysaccharidePhosphate-buffered salineMouse modelImmune regulationrecombinant mouseUlcerative colitismesenteric lymph node
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Authors
Miranda L. Hanson, Julie A. Hixon, Wenqing Li, Barbara K. Felber, Miriam R. Anver, C. Andrew Stewart, Brian M. Janelsins, Sandip K. Datta, Wei Shen, Mairi H. McLean, Scott K. Durum,