Hepatic Cell-Type Specific Gene Expression Better Predicts HCV Treatment Outcome Than IL28B Genotype

Article ID	Journal	Published Year	Pages	File Type
3292891	Gastroenterology	2012	11 Pages	PDF

Abstract

The cell-type-specific expression pattern of ISGs varies among patients with different IL28B genotypes and is a strong predictor of response to interferon-based treatment.

Keywords

mecA SVR ISG AIC KNN PPV MxA CART DAA k-nearest neighbor positive predictive value negative predictive value Direct-acting antiviral Liver disease Classification and regression tree Prognostic factor Akaike's Information Criterion NPV یا negative predictive value Treatment outcome Sustained virologic response Single nucleotide polymorphism SNP interferon-stimulated gene

Related Topics

Health Sciences Medicine and Dentistry Gastroenterology

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Hepatic Cell-Type Specific Gene Expression Better Predicts HCV Treatment Outcome Than IL28B Genotype

Authors

Ian McGilvray, Jordan J. Feld, Limin Chen, Venessa Pattullo, Maha Guindi, Sandra Fischer, Ivan Borozan, Gang Xie, Nazia Selzner, E. Jenny Heathcote, Katherine Siminovitch,