| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3293097 | Gastroenterology | 2012 | 14 Pages |
Abstract
Upon binding to apical CD71, SIgA (with or without gliadin peptides) enters a recycling pathway and avoids lysosomal degradation; this process allows apical-basal transcytosis of bound peptides. This mechanism is facilitated by Tgase2 and might be involved in the pathogenesis of celiac disease.
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Authors
Corinne Lebreton, Sandrine Ménard, Juliette Abed, Ivan Cruz Moura, Rosanna Coppo, Christophe Dugave, Renato C. Monteiro, Aurélie Fricot, Meriem Garfa Traore, Martin Griffin, Christophe Cellier, Georgia Malamut, Nadine Cerf-Bensussan, Martine Heyman,