| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3293099 | Gastroenterology | 2012 | 13 Pages |
Abstract
Defective interactions between WASP-deficient innate immune cells and normal T cells disrupt mucosal regulation, potentially by altering the functions of tolerogenic dendritic cells, production of interleukin-10, and homeostasis of regulatory T cells.
Keywords
FACSRAGCDCPDCGFPTregTNFRecombination activating gene 2TGFMLNWASPRT-PCRMϕantigen-presenting cellsinterleukinBrdUbromodeoxyuridineInflammatory bowel diseasetransforming growth factorRegulatory T cellDendritic cellPlasmacytoid dendritic cellconventional dendritic celltumor necrosis factorfluorescence-activated cell sorterLamina propriaMouse modelMonocytes/macrophagesknockoutwild-typereverse-transcription polymerase chain reactionWiskott–Aldrich syndrome proteingreen fluorescent proteinImmunodeficiencymesenteric lymph node
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Authors
Deanna D. Nguyen, Marc-Andre Wurbel, Jeremy A. Goettel, Michelle A. Eston, Osub S. Ahmed, Romela Marin, Elisa K. Boden, Eduardo J. Villablanca, Helena Paidassi, Vineet Ahuja, Hans-Christian Reinecker, Edda Fiebiger, Adam Lacy-Hulbert,