Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3293195 | Gastroenterology | 2014 | 26 Pages |
Abstract
ADAM10 acts in a cell autonomous manner within the intestinal crypt compartment to regulate Notch signaling. This process is required for progenitor cell lineage specification and crypt-based columnar cell maintenance.
Keywords
CBCNeurog3MMP7CBCsLGR5NICDYFPISCADAM10eGFPDllIntestinal epitheliumtamoxifenDifferentiationIntraperitoneallyNotch intracellular domainDevelopmentintestinal stem celldelta-like ligandMatrix metalloproteinase-7Neurogenin-3yellow fluorescent proteinenhanced green fluorescent proteina disintegrin and metalloproteinase domain-containing protein 10
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Authors
Yu-Hwai Tsai, Kelli L. VanDussen, Eric T. Sawey, Alex W. Wade, Chelsea Kasper, Sabita Rakshit, Riha G. Bhatt, Alex Stoeck, Ivan Maillard, Howard C. Crawford, Linda C. Samuelson, Peter J. Dempsey,