| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3293197 | Gastroenterology | 2014 | 24 Pages |
Abstract
In human CRC cells, miR-221 and miR-222 act in a positive feedback loop to increase expression levels of RelA and STAT3. Antagonism of miR-221 and miR-222 reduces growth of colon tumors in mice with colitis.
Keywords
STAT3NF-κBTNFDSSmRNACACmessenger RNAinterleukinterminal deoxynucleotidyl transferase–mediated deoxyuridine triphosphate nick-end labelingTUNELColorectal cancercolitis-associated cancerColon cancerCarcinogenesisdextran sodium sulfatetumor necrosis factornuclear factor κBsignal transducer and activator of transcription 3UTR یا untranslated regions untranslated regionMicroRNAMiRNACRC
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Authors
Sanhong Liu, Xiaohua Sun, Mingliang Wang, Yingyong Hou, Yu Zhan, Yuhang Jiang, Zhanjie Liu, Xinwei Cao, Pengfei Chen, Zhi Liu, Xi Chen, Yu Tao, Chen Xu, Jie Mao, Chunyan Cheng, Cuifeng Li, Yiming Hu, Lunshan Wang, Xiaoren Zhang,