| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3293199 | Gastroenterology | 2014 | 20 Pages |
Abstract
Protection from persistent HCV reinfection depends on the magnitude, breadth, and quality of the HCV-specific memory T-cell response. Sequence homology among viruses and ability of T cells to recognize multiple strains of HCV are critical determinants of protective memory.
Keywords
TNFαELISPOTTregPBMCSFCICSEnzyme-linked immunospot assayProtective immunityinterferonIFNtumor necrosis factor alphaintracellular cytokine stainingRegulatory T cellSpot-forming cellPeripheral blood mononuclear cellCytokinesViral infectionInjection drug usersIDUsImmune regulationHCVHepatitis C virushuman immunodeficiency virusHIV
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Authors
Mohamed S. Abdel-Hakeem, Nathalie Bédard, Donald Murphy, Julie Bruneau, Naglaa H. Shoukry,