Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3293225 | Gastroenterology | 2013 | 10 Pages |
Abstract
The endocrine and exocrine cells in the adult pancreas are not static, but can change their differentiation state in response to injury or stress. This concept of cells in flux means that there may be ways to generate certain types of cells (such as insulin-producing β-cells) and prevent formation of others (such as transformed neoplastic cells). We review different aspects of cell identity in the pancreas, discussing how cells achieve their identity during embryonic development and maturation, and how this identity remains plastic, even in the adult pancreas.
Keywords
Related Topics
Health Sciences
Medicine and Dentistry
Gastroenterology
Authors
Ben Z. Stanger, Matthias Hebrok,