| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3293272 | Gastroenterology | 2013 | 24 Pages |
Abstract
In patients with chronic HCV infection, IFN production by Kupffer cells might promote innate immune tolerance, characterized by a lack of response to IFN therapy. Strategies to disrupt the virus-host interactions that induce innate immune tolerance should improve therapy.
Keywords
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Authors
Daryl T.-Y. Lau, Amina Negash, Jie Chen, Nanette Crochet, Mala Sinha, Yuhong Zhang, Jeremie Guedj, Sharon Holder, Takeshi Saito, Stanley M. Lemon, Bruce A. Luxon, Alan S. Perelson, Michael Jr,