Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3293391 | Gastroenterology | 2013 | 13 Pages |
Abstract
Ts cells isolated from patients with CD have a reduced ability to suppress proliferation of CD4+T cells compared with control Ts cells. TGF-β signaling reduces the suppressor activity of Ts cells.
Keywords
PBMCEndoglinSuppressor T cellLPLCFSETGFENGchromatin immunoprecipitationinterferonIFNinterleukinInflammatory bowel diseasetransforming growth factorRegulatory T cellTreg cellPeripheral blood mononuclear cellintestinal epithelial cellTreg cellsRegulatory T cellsNormalLamina proprialamina propria lymphocyteImmune regulationCHiPcarboxyfluorescein succinimidyl esterIEC
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Authors
Keren M. Rabinowitz, Yuanyuan Wang, Edward Y. Chen, Zara Hovhannisyan, David Chiang, M. Cecilia Berin, Stephanie Dahan, Damien Chaussabel, Avi Ma'ayan, Lloyd Mayer,