Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3293552 | Gastroenterology | 2012 | 11 Pages |
Abstract
Deiodinases are at the interface between the β-catenin and the thyroid hormone pathways. Their synchronized regulation of intracellular T3 concentration is a hitherto unrecognized route by which the multiple effects of β-catenin are generated and may be targeted to reduce the oncogenic effects of β-catenin in intestinal cells.
Keywords
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Gastroenterology
Authors
Monica Dentice, Cristina Luongo, Raffaele Ambrosio, Annarita Sibilio, Antonella Casillo, Antonino Iaccarino, Giancarlo Troncone, Gianfranco Fenzi, P. Reed Larsen, Domenico Salvatore,