Loss of Glucagon-Like Peptide-2-Induced Proliferation Following Intestinal Epithelial Insulin-Like Growth Factor-1-Receptor Deletion

Article ID	Journal	Published Year	Pages	File Type
3293622	Gastroenterology	2011	17 Pages	PDF

Abstract

The proliferative responses of the intestinal epithelium to exogenous GLP-2 administration and conditions of GLP-2-dependent adaptive re-growth require the intestinal epithelial IGF-1R.

Keywords

IGF mRNA qRT-PCR ERBB GLP-2R messenger RNA Growth Small intestine intestinal epithelial cell Signaling Insulin-like growth factor Mouse model quantitative reverse-transcription polymerase chain reaction IEC

Related Topics

Health Sciences Medicine and Dentistry Gastroenterology

Preview

Loss of Glucagon-Like Peptide-2-Induced Proliferation Following Intestinal Epithelial Insulin-Like Growth Factor-1-Receptor Deletion

Authors

Katherine J. Rowland, Shivangi Trivedi, Daiyoon Lee, Ken Wan, Rohit N. Kulkarni, Martin Holzenberger, Patricia L. Brubaker,