Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3293751 | Gastroenterology | 2011 | 16 Pages |
Abstract
TP53 mutations, particularly the hot spot mutations R249S and V157F, are associated with poor prognosis for patients with HCC. The acquisition of stem cell-like gene expression traits might contribute to the aggressive behavior of tumors with TP53 mutation.
Keywords
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Authors
Hyun Goo Woo, Xin Wei Wang, Anuradha Budhu, Yun Hee Kim, So Mee Kwon, Zhao-You Tang, Zongtang Sun, Curtis C. Harris, Snorri S. Thorgeirsson,