Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3293812 | Gastroenterology | 2012 | 10 Pages |
Abstract
We identified variants in PPIA that destabilize its product, CypA, and prevent HCV infection and replication. These findings indicate mechanisms by which some cells might be resistant to HCV infection and that CypA is a good therapeutic target.
Keywords
Related Topics
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Gastroenterology
Authors
Thomas von Hahn, Cordelia Schiene-Fischer, Nguyen Dinh Van, Stephanie Pfaender, Behya Karavul, Eike Steinmann, Andrej Potthoff, Christian Strassburg, Nabila Hamdi, Ahmed I. Abdelaziz, Christoph Sarrazin, Tobias Müller, Thomas Berg, Eric Trépo,