Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3293870 | Gastroenterology | 2012 | 23 Pages |
Abstract
In livers of mice, expression of NEMO and activation of NF-κB are required for hepatocyte proliferation and liver regeneration. These mechanisms require control of oxidative stress and DNA integrity.
Keywords
IL6RDAPIiNOSBHAMnSODIKKFHCPEITCTNFDSBNF-κB4′,6-diamidino-2-phenylindole5-bromo-2′-deoxyuridineddCIκB kinaseROSImmunohistochemistryIHCTeminterleukinTissue regenerationBrdUterminal deoxynucleotidyl transferase–mediated deoxyuridine triphosphate nick-end labelingLiver diseaseTUNELFerritin Heavy Chaininducible nitric oxide synthasemanganese superoxide dismutasedouble-strand breakneutrophil cytosolic factor 1tumor necrosis factornuclear factor κBMouse modelTransmission electron microscopyPartial hepatectomybutylated hydroxyanisolePhenethyl isothiocyanateReactive oxygen speciesInterleukin-6 receptor
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Authors
Yann Malato, Haksier Ehedego, Malika Al-Masaoudi, Francisco Javier Cubero, Jörn Bornemann, Nikolaus Gassler, Christian Liedtke, Naiara Beraza, Christian Trautwein,