| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3293876 | Gastroenterology | 2012 | 17 Pages |
Abstract
Notch signaling is activated in human HCC samples and promotes formation of liver tumors in mice. The Notch signature is a biomarker of response to Notch inhibition in vitro.
Keywords
NICDIGF2GSIGFPNTPmRNAHCCmessenger RNAα-fetoproteinImmunohistochemistryIHCAFPNotch intracellular domaininsulin-like growth factor 2genetically engineered mouse modelgene expression profilingγ-secretase inhibitorHCVHepatitis C viruspolymerase chain reactionPCRgreen fluorescent proteinHepatocellular carcinoma
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Authors
Augusto Villanueva, Clara Alsinet, Kilangsungla Yanger, Yujin Hoshida, Yiwei Zong, Sara Toffanin, Leonardo Rodriguez-Carunchio, Manel Solé, Swan Thung, Ben Z. Stanger, Josep M. Llovet,