Regional Gray Matter Density Changes in Brains of Patients With Irritable Bowel Syndrome

Article ID	Journal	Published Year	Pages	File Type
3293922	Gastroenterology	2010	12 Pages	PDF

Abstract

Changes in density of gray matter among regions involved in cognitive/evaluative functions are specifically observed in patients with IBS, whereas changes in other areas of the brain can be explained by levels of anxiety and depression.

Keywords

UCLA PAG MFG VBM OFC DSM-IV IBS aMCC GLM CTA GMD PFC INS ACC University of California Los Angeles MRI Magnetic resonance imaging Neuroimaging insula periaqueductal gray diagnostic and statistical manual of mental disorders 4th edition irritable bowel syndrome cortical thickness Neural prefrontal cortex orbitofrontal cortex anterior cingulate cortex anterior midcingulate cortex Secondary somatosensory cortex Gray matter CSF Cerebrospinal fluid General linear model Brodmann area voxel-based morphometry Gray matter density middle frontal gyrus