Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3293937 | Gastroenterology | 2010 | 11 Pages |
Abstract
Acid and bile salts induce CDX2 mRNA and protein expression in esophageal squamous cells from patients with Barrett's esophagus, but not from GERD patients without Barrett's esophagus. We speculate that these differences in acid- and bile salt-induced activation of molecular pathways may underlie the development of Barrett's metaplasia.
Keywords
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Gastroenterology
Authors
Xiaofang Huo, Hui Ying Zhang, X.I. Zhang, John P. Lynch, Eric D. Strauch, Jian-Ying Wang, Shelby D. Melton, Robert M. Genta, David H. Wang, Stuart J. Spechler, Rhonda F. Souza,