| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3293945 | Gastroenterology | 2010 | 11 Pages |
Abstract
Because HLA-DR*0405 expression fails to protect mice from AIP, the HLA-DRB1*0405 allele appears to be an important risk factor for AIP on the HLA-DRB1*0405/DQB1*0401 haplotype. This humanized mouse model should be useful for studying immunopathogenesis, diagnostic markers, and therapy of human AIP.
Keywords
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Authors
Tobias L. Freitag, Candace Cham, Hsiang-Hsuan Sung, Georg F. Beilhack, Ivana Durinovic-Belló, Salil D. Patel, Roderick T. Bronson, Detlef Schuppan, Grete Sønderstrup,