Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3293947 | Gastroenterology | 2010 | 13 Pages |
Abstract
Taken together, our in vitro and in vivo data suggest that increasing intracellular calcium by Trpv4 activation may represent a potential therapeutic approach in PKD.
Keywords
3-D4αPDDNRCSPKDADPKDCholangiocytesARPKDnIFCCLTRPVTRPV4eGFP3-dimensional4α-phorbol 12,13-didecanoateSmall interfering RNAsiRNAArachidonic acidautosomal-dominant polycystic kidney diseaseautosomal-recessive polycystic kidney diseaseEETNifedipinetransient receptor potential vanilloidenhanced green fluorescent proteinCalcium
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Authors
Sergio A. Gradilone, Tatyana V. Masyuk, Bing Q. Huang, Jesus M. Banales, Guillermo L. Lehmann, Brynn N. Radtke, Angela Stroope, Anatoliy I. Masyuk, Patrick L. Splinter, Nicholas F. LaRusso,