Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3294010 | Gastroenterology | 2012 | 13 Pages |
Abstract
The increased level of arginase in patients with acute hepatitis B suppresses the functions of activated CD8+ T cells. This mechanism might limit the amount of liver damage caused by activated CD8+ T cells in patients with acute HBV infection.
Keywords
PBMCTNFAHBHCMVICSTCrGFPEBVinterferonIFNinterleukinLiver diseaseAcute Hepatitis BTreatmentintracellular cytokine stainingPeripheral blood mononuclear cellCMVcytomegalovirusHuman cytomegalovirusPatienttumor necrosis factorImmune regulationEpstein–Barr virusvirologygreen fluorescent proteinT-cell receptor
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Authors
Elena Sandalova, Diletta Laccabue, Carolina Boni, Tsunamasa Watanabe, Anthony Tan, Ho Zi Zong, Carlo Ferrari, Antonio Bertoletti,