Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3294015 | Gastroenterology | 2012 | 16 Pages |
Abstract
We have identified a pathway by which villus epithelial cells are maintained during C parvum infection. Loss of barrier function is reduced by active retention of infected enterocytes until they reach the villus tip. These findings might be used to promote clearance of minimally invasive enteropathogens, such as by increasing the rate of migration of epithelial cells from the crypt to the villus tip.
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Authors
Derek M. Foster, Stephen H. Stauffer, Maria R. Stone, Jody L. Gookin,