| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3294019 | Gastroenterology | 2012 | 19 Pages |
Abstract
miR-375 inhibits autophagy by reducing expression of ATG7 and impairs viability of HCC cells under hypoxic conditions in culture and in mice. miRNAs that inhibit autophagy of cancer cells might be developed as therapeutics.
Keywords
PDK1mTORGFPmRNAHCCmessenger RNASmall interfering RNAsiRNATemGene expressionLiver cancerCell deathUTR یا untranslated regions untranslated regionMicroRNAMiRNATransmission electron microscopymammalian target of rapamycinpolymerase chain reactionPCRmRNA processinggreen fluorescent proteinHepatocellular carcinoma
Related Topics
Health Sciences
Medicine and Dentistry
Gastroenterology
Authors
Ying Chang, Wei Yan, Xingxing He, Lemeng Zhang, Chuanjiang Li, Hai Huang, Gary Nace, David A. Geller, Jusheng Lin, Allan Tsung,