| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3294132 | Gastroenterology | 2012 | 16 Pages |
Abstract
The nucleotide synthesis enzyme CAD is a negative regulator of NOD2. The antibacterial function of NOD2 variants that have been associated with CD increased in response to pharmacologic inhibition of CAD. CAD is a potential therapeutic target for CD.
Keywords
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Gastroenterology
Authors
Amy L. Richmond, Amrita Kabi, Craig R. Homer, Noemà Marina-GarcÃa, Kourtney P. Nickerson, Alexey I. Nesvizhskii, Arun Sreekumar, Arul M. Chinnaiyan, Gabriel Nuñez, Christine McDonald,