| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3294133 | Gastroenterology | 2012 | 17 Pages |
Abstract
Autophagy is induced upon formation of the immunologic synapse and negatively regulates T-cell activation. This mechanism might increase adaptive immunity in patients with Crohn's disease who carry ATG16L1 risk alleles.
Keywords
GFPSMACmTORBMDCT helperICAM-1Th17OVA3-MA3-methyladenineSmall interfering RNAsiRNAOvalbumininterleukinInflammatory bowel diseaseCellular interactionsDendritic cellBone marrow–derived dendritic cellmajor histocompatibility complexMHCImmune regulationIntercellular adhesion molecule 1green fluorescent protein
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Authors
Manon E. Wildenberg, Anne Christine W. Vos, Simone C.S. Wolfkamp, Marjolijn Duijvestein, Auke P. Verhaar, Anje A. Te Velde, Gijs R. van den Brink, Daniel W. Hommes,