| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3294136 | Gastroenterology | 2012 | 16 Pages |
Abstract
Blocking Th17 allows ngTregs to differentiate into functionally stable immune inhibitory cells; this approach might be developed for therapy of patients with AIH.
Keywords
T-helperrIL-2AIHPBMCTregTGFMFISmall interfering RNAsiRNAanti-nuclear antibodyanti–smooth muscle antibodyANAHealthy subjectsLiver inflammationimmunotherapyinterferonIFNinterleukinRecombinant interleukin-2transforming growth factorT-cell developmentSMAPeripheral blood mononuclear cellT regulatory cellImmune regulationmean fluorescence intensityAutoimmune hepatitis
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Authors
Maria Serena Longhi, Rodrigo Liberal, Beth Holder, Simon C. Robson, Yun Ma, Giorgina Mieli-Vergani, Diego Vergani,