| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3294141 | Gastroenterology | 2012 | 17 Pages |
Abstract
Cftrâ/â and CftrÎF508 mice have defects in gallbladder emptying that disrupt enterohepatic circulation of BAs. These defects create a shunt pathway that restricts the amount of toxic secondary BAs that enter the liver.
Keywords
ileal bile acid-binding proteinOSTα/βIBABPmRNACyPNtcpCFTRFGFSHPVIPCCKcAMPmessenger RNAadenosine 3′,5′-cyclic monophosphateAsbtBile acidBicarbonate secretionTechnetiumBile acid transporterscystic fibrosis transmembrane conductance regulatorCytochrome P450small heterodimer partnerfibroblast growth factorCystic fibrosishigh-performance liquid chromatographyHPLCcholecystokininEnterohepatic circulation
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Authors
Dominique Debray, Dominique Rainteau, Véronique Barbu, Myriam Rouahi, Haquima El Mourabit, Stéphanie Lerondel, Colette Rey, Lydie Humbert, Dominique Wendum, Charles-Henry Cottart, Paul Dawson, Nicolas Chignard, Chantal Housset,