Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3294194 | Gastroenterology | 2010 | 11 Pages |
Abstract
CDC accelerates colonic transit and improves bowel function in female patients with IBS-C. The rate of bile acid synthesis influences colonic transit. Genetic variation in negative feedback inhibition of bile acid synthesis may affect CDC-mediated acceleration of colonic transit.
Keywords
IBS-CFGF19FGFR4CDCMAFt½ANCOVA7α-hydroxy-4-cholesten-3-oneBile acidanalysis of covariancebody mass indexBMIAscendingfibroblast growth factor 19minor allele frequencygeometric centerHalf-lifeSingle nucleotide polymorphismSNPKlbfibroblast growth factor receptor 4Constipation-predominant irritable bowel syndrome
Related Topics
Health Sciences
Medicine and Dentistry
Gastroenterology
Authors
Archana S. Rao, Banny S. Wong, Michael Camilleri, Suwebatu T. Odunsi-Shiyanbade, Sanna McKinzie, Michael Ryks, Duane Burton, Paula Carlson, Jesse Lamsam, Ravinder Singh, Alan R. Zinsmeister,