Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
3294196 | Gastroenterology | 2010 | 16 Pages |
Abstract
A GWAS significantly associated genetic variants with features of hepatic histology in patients with NAFLD. These findings should be validated in larger and more diverse cohorts.
Keywords
FDFT1HbA1cIQRPNPLA3NASALTpdgfaFDRNRELXR-αCRNPZPTGF-βGGTNAFLDASTAspartate aminotransferaseAlanine aminotransferaseALPAlkaline phosphatasenonalcoholic steatohepatitisNonalcoholic fatty liver diseasetransforming growth factor-βMagnetic resonancebody mass indexBMIClinical Research Networkinterquartile rangeGenome-wide association studyGWASfalse discovery rateNAFLD activity scoreNash Glycated hemoglobinSingle nucleotide polymorphismSNPliver X receptor α
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Authors
Naga Chalasani, Xiuqing Guo, Rohit Loomba, Mark O. Goodarzi, Talin Haritunians, Soonil Kwon, Jinrui Cui, Kent D. Taylor, Laura Wilson, Oscar W. Cummings, Yii-Der Ida Chen, Jerome I. Rotter,