| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3294204 | Gastroenterology | 2010 | 18 Pages |
Abstract
This study describes a novel model of experimental colitis that highlights the importance of PI3K p110δ in maintaining mucosal homeostasis and could provide insight into the pathogenesis of human inflammatory bowel disease.
Keywords
PI3KhpfBMMTLRGAPDHSPFLPMCLPSPI3-kinaseTNFInnate immunityinterferonIFNinterleukingerm-freeinflammatory bowel diseasesELISAEnzyme-linked immunosorbent assayToll-like receptorspecific pathogen-freelamina propria mononuclear celltumor necrosis factorphosphoinositide 3-kinaselipopolysaccharideBone marrow–derived macrophagehigh-power fieldmapwild-typepolymerase chain reactionPCRmitogen-activated proteinglyceraldehyde-3-phosphate dehydrogenase
Related Topics
Health Sciences
Medicine and Dentistry
Gastroenterology
Authors
Jennifer K. Uno, Kavitha N. Rao, Katsuyoshi Matsuoka, Shehzad Z. Sheikh, Taku Kobayashi, Fengling Li, Erin C. Steinbach, Antonia R. Sepulveda, Bart Vanhaesebroeck, R. Balfour Sartor, Scott E. Plevy,