| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3294206 | Gastroenterology | 2010 | 22 Pages |
Abstract
Loss of Ihh initiates several events that are characteristic of an intestinal wound repair response. Prolonged loss resulted in progressive inflammation, mucosal damage, and the development of intestinal fibrosis. Ihh is a signal derived from the superficial epithelial cells that may act as a critical indicator of epithelial integrity.
Keywords
Patched1PTCH1GliIHHPAI-1SSCHRPTGFβRT-PCRα-SMAstandard saline citrateinflammationglioma-associated oncogeneα-smooth muscle actinRegenerationBrdUbromodeoxyuridinetransforming growth factor-βHedgehogIndian HedgehogIntestineBMPPlasminogen activator inhibitor-1Hhipreverse-transcription polymerase chain reactionHorseradish peroxidasehedgehog-interacting proteinBone morphogenetic protein
Related Topics
Health Sciences
Medicine and Dentistry
Gastroenterology
Authors
Willemijn A. van Dop, Jarom Heijmans, Nikè V.J.A. Büller, Susanne A. Snoek, Sanne L. Rosekrans, Elisabeth A. Wassenberg, Marius A. van den Bergh Weerman, Beate Lanske, Alan R. Clarke, Douglas J. Winton, Mark Wijgerde, G. Johan Offerhaus,