| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 3294209 | Gastroenterology | 2010 | 14 Pages |
Abstract
UGT1A genes are induced in vitro and in vivo by coffee, independent of caffeine content, cafestol, or kahweol. Coffee up-regulates glucuronidation by AhR signaling and Nrf2 binding to the ARE/XRE. Glucuronidation could mediate the protective and antioxidant effects of coffee.
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Authors
Sandra Kalthoff, Ursula Ehmer, Nicole Freiberg, Michael P. Manns, Christian P. Strassburg,